1. | A RECENT REVIEW ON IMPORTANCE OF INDOLE IN THE FIELD OF MEDICINAL CHEMISTRY |
| Theivendren Panneerselvama*, Sajan Francis Pa, Adarsha Govinda Ka
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Indole motif is a vital part in many of the naturally and synthetically available medicinal compounds and they are well known for their biological significance because of its aptitude to tempt harmful cell inhibition in many of the diseases cell lines. The current review covers past five years of period indole achievements in connection of its biological activities. The aim of review is addresses the importance of indole derivatives in the field of medicinal drug discovery.
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2. | PRESCRIPTION AUDITING AND COST COMPARISON ANALYSIS OF CHEMOTHERAPEUTIC AGENTS IN AN ONCOLOGY UNIT OF A TERTIARY CARE TEACHING HOSPITAL |
| Jasteena Jose, Dinesh Shet, Rohan Fernandes, Riyaz Ahamed, Theivendren Panneerselvam
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The main aim of this study is to monitor the appropriateness of various parameters in the prescription and selection of suitable of brand of chemotherapeutic agents. Prescription audit is a technique and its application is science as well as an art. The objectives are to observe the different types of prescription audit parameters and to study cost comparison analysis of various brands of chemotherapeutic agents. It can inform the appropriateness of various parameters in the prescription and the average number of drugs per prescription. It can provide the socio-demographic characteristics of patients in the oncology unit. The background of current study was conducted at tertiary care teaching hospital of Karnataka. It was an observational study performed in 300 prescriptions and 150 cases from 3 pharmacies and an oncology unit for a period of 6 months. Daily visit was made on pharmacy and wards for data collection. Prescription auditing showed that 100% name, 94% age, 76% date and duration mentioned in 87% and in an average, there are 4 drugs per prescription. Commonly prescribed high cost onco drugs are Paclitaxel Rs.4236 (Cipla Company) and Ristova Rs.35704.98 (Roche Company). Prescription audit is an important mechanism to improve the quality of care afforded by the hospitals. The observed results of auditing showed that the prevailing prescribing habits of the institution and it are very essential to improve prescribing habits. The conducted study was helped to improve ability of pharmacists to demonstrate competence, to be aware of levels of competence and to identify learning needs further exploration.
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3. | CURRENT REVIEW ON IMPORTANCE OF IMIDAZOLE DERIVATIVES |
| Theivendren Panneerselvama, Adarsha Govinda K, Sajan Francis P
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Imidazole motif is a vital part in many of the naturally and synthetically available medicinal compounds and they are well known for their biological significance because of its aptitude to tempt harmful cell inhibition in many of the diseases cell lines. The current review covers about past five years of period indole achievements in connection of its biological activities. The aim of review is addresses the importance of imidazole derivatives in the field of medicinal drug discovery.
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