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ABSTRACT Patients with type 2 diabetes have an increased prevalence of lipid abnormalities. A timely intervention to normalize circulating lipids could reduce the chances of cardiovascular complications. This aim was to evaluate the frequency and pattern of dyslipidemia and effect of age on alteration of lipid profile in male type 2 diabetes. A prospective study was conducted for investigation of the serum lipid profile viz the level of total cholesterol, Triglycerides, LDL cholesterol and HDL cholesterol and compare them with non obese non diabetic and normotensive control. The result revealed that serum total cholesterol, LDL cholesterol and triglycerides were significantly raised (p<0.001) where as the level of HDL cholesterol was significantly lower (p<0.001) in diabetic subjects as compared to control. The fasting blood sugar level of the diabetics was significantly higher (P < 0.001) than those of the controls. 21% diabetics in this study had hypercholesterolemia, 58% hypertriglyceridemia, 18% abnormal LDL levels and in 17% the HDL was less than 40 mg/dl. 63% of diabetic patients were dyslipidemic as compared with 12% of control patients. Of the dyslipidemic diabetic subjects (70%) were aged >50 years. Serum total cholesterol and LDL cholesterol were significantly raised (P< 0.001) where as the level of HDL cholesterol was significantly lower (P< 0.0049) in diabetic subjects aged more than 50 years as compared to diabetic subjects aged less than 50 years revealing increasing age is associated with severe and higher risk of dyslipidemia. The frequencies of high TC, high TG, and high LDL were higher in the diabetic group and thus indicating that diabetic patients are more prone to dyslipidemia which could cause cardiovascular disease. Thus lipid profile analysis must be made an integral part of type 2 DM patients’ clinical reviews and treatment. Therefore early detection good glycaemic control can prevent development and progression of lipid-abnormalities among patients with diabetes mellitus. Key Words:- Diabetes, cholesterol, triglycerides, HDL cholesterol and LDL cholesterol.

ABSTRACT The lungs are vital organs. Working with the heart and circulatory system, they provide life-sustaining oxygen and rid the body of carbon dioxide. Normal lungs have a great reserve capacity to meet the body‘s need for oxygen across a wide variety of circumstances. The same is true of the heart and circulatory system. This reserve capacity permits cancerous lung tumors to grow for years without compromising lung function. Furthermore, the lungs do not have many nerves to transmit pain messages. Therefore, a cancerous lung tumor can grow for many years without causing any symptoms. Lungs cancer is the fatal disease in worldwide. The prognosis of lungs cancer is generally favorable. Non small cell lungs cancer is regarded as life threatening disease occurred mostly than other types. Hence early diagnosis and quick treatment is essential. Normally surgery, radiation therapy and chemotherapy allow a good prognosis for non small cell lungs cancer. Key Words:- Non small cell lungs cancer, Prognosis, Diagnosis.

ABSTRACT The Staphylococcus aureus local isolated no 10. was carrying luk gene, which choose to produced staphylokinase and purification by different methods like ion Exchange-Chromatography and Gel Filtration Chromathography were used. The molecular weight of the native staphylokinase was determined by chromatography through Sephorase 6B column and by SDS polyacrylamide gel and estimated as 15,848 KD, isoelectric focusing in polyacrylamide gel was used to determine the iso electric point (PI) value and estimated as 6.3. Key words: Staphylokinase, Staphylococcus aureus, Purification of Staphylokinase, Isoelectric point.

ABSTRACT Heatstroke is a very common clinical emergency in hot areas. In absence of timely and effective intervention, it may progress to death. The pathophysiological mechanisms underlying heatstroke in dry-heat environment of deserts has not been thoroughly investigated (ou Zhou et al., 2014). A strong association has been observed between heat stroke and acute liver failure (Garcin et al., 2008) suggesting that hepatic function indicators can serve as potential heat stress biomarkers. We have established rat models of acute heat stress and heatstroke simulating dry-heat environment of desert, to assess the impact of graded heat stress on Liver function indicators. With acute heat stress progressing to heat stroke, the liver damage changed from mild to serious as concluded by assessing blood enzymology parameters such as alanine aminotransferase and aspartate aminotransferase etc. This suggests the applicability of hepatic damage blood enzymology as a potential heat stroke diagnostic tool. Key Words:- Heat Stroke, Acute heat stress, Liver function test, Biochemical analysis.

ABSTRACT Previous studies showed that medicinal plants exerted a wide range of antibacterial activity. These plants included: Achillea santolina, Adiantum capillus-veneris, Agrimonia eupatoria, Agropyron repens, Ailanthus altissima, Alhagi maurorum, Allium cepa, Allium porrum, Allium sativum, Allium schoenoprasum, Alpinia galangal, Althaea officinalis, Althaea rosea, Ammannia baccifera, Ammi visnaga, Anagyris foetida, Anchusa strigosa, Anethum graveolens, Anthemis nobelis, Antirrhinum majus, Apium graveolens, Arachis hypogaea, Arctium lappa, Artemisia campestris, Arundo donax, Asclepias curassavica, Asparagus officinalis, Avena sativa, Bacopa monniera, Ballota nigra, Bauhinia variegata, Bellis perenni, Benincasa hispida, Betula alba, Bidens tripartite, Brassica rapa, Bryophyllum calycinum, Caesalpinia crista, Calamintha graveolens, Calendula officinalis, Calotropis procera, Canna indica, Capparis spinosa, Capsella bursa-pastoris, Capsicum annuum, Capsicum frutescens, Carthamus tinctorius, Carum carvi, Cassia occidentalis, Casuarina equisetifolia, Celosia cristata, Centaurea cyanus, Chenopodium album and Chrozophora tinctoria. This review was designed to highlight the antibacterial effects of these medicinal plants. Key Words:- Medicinal plants, Antibacterial, Pharmacognosy, Pharmacology, Therapeutics.

ABSTRACT Previous studies showed that a wide range of medicinal plants exerted antioxidant activity. These plants included: Achillea santolina, Adiantum capillus-veneris, Agrimonia eupatoria, Ailanthus altissima, Alhagi maurorum, Allium cepa, Allium porrum, Allium sativum, Allium schoenoprasum, Alpinia galangal, Althaea officinalis, Ammannia baccifera, Ammi visnaga, Anchusa italica, Anchusa strigosa, Anethum graveolens, Antirrhinum majus, Arachis hypogaea, Arctium lappa, Artemisia campestris, Asparagus officinalis, Astragalus hamosus, Avena sativa, Bacopa monniera, Ballota nigra, Bauhinia variegata, Bellis perenni, Bidens tripartite, Brassica rapa, Bryophyllum calycinum, Caesalpinia crista Calamintha graveolens, Calendula officinalis, Calotropis procera, Canna indica, Capparis spinosa, Capsicum annuum, Capsicum frutescens, Carthamus tinctorius, Carum carvi, Cassia occidentalis, Casuarina equisetifolia, Centaurea cyanus, Chenopodium album and Chrozophora tinctoria. This review was designed to highlight the antioxidant effects of these medicinal plants. Key Words:- Medicinal plants, Antioxidant, Pharmacognosy, Pharmacology, Therapeutics.